John R Asplin Selected Research

Oxalates

12/2021	Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion.
1/2021	Evidence for abnormal linkage between urine oxalate and citrate excretion in human kidney stone formers.
1/2021	Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease.
11/2017	Impact of Regular or Extended Hemodialysis and Hemodialfiltration on Plasma Oxalate Concentrations in Patients With End-Stage Renal Disease.
1/2017	Steatorrhea and Hyperoxaluria in Severely Obese Patients Before and After Roux-en-Y Gastric Bypass.
1/2017	Loss of Cystic Fibrosis Transmembrane Regulator Impairs Intestinal Oxalate Secretion.
2/2016	The management of patients with enteric hyperoxaluria.
2/2016	Prospective evaluation of urinary metabolic indices in severely obese adolescents after weight loss surgery.
11/2013	NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy.
12/2011	Variability in urinary oxalate measurements between six international laboratories.

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John R Asplin Research Topics

Disease

24	Kidney Calculi (Kidney Stone) 01/2022 - 03/2002
17	Nephrolithiasis 01/2021 - 03/2002
12	Hyperoxaluria (Oxaluria) 01/2017 - 12/2002
7	Hypercalciuria 12/2015 - 03/2002
5	Cystinuria 12/2019 - 04/2005
5	Urolithiasis 08/2019 - 04/2006
4	Urinary Calculi (Urinary Calculus) 01/2019 - 05/2002
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019 - 01/2009
3	Obesity 01/2017 - 02/2007
3	Bone Resorption 12/2015 - 10/2013
2	Acidosis 01/2021 - 10/2020
2	Weight Loss (Weight Reduction) 08/2019 - 01/2009
2	Insulin Resistance 01/2019 - 01/2009
2	Chronic Disease (Chronic Diseases) 12/2016 - 03/2015
2	Chronic Renal Insufficiency 01/2014 - 02/2011
2	Primary Hyperoxaluria (Oxaluria, Primary) 11/2013 - 12/2002
2	Renal Insufficiency (Renal Failure) 11/2013 - 02/2007
1	Infections 01/2022
1	Pain (Aches) 10/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Crohn Disease (Crohn's Disease) 01/2021
1	Calcium Oxalate Nephrolithiasis 01/2021
1	Diabetes Mellitus 01/2021
1	Nephrocalcinosis 01/2021
1	Diarrhea 10/2020
1	Hypophosphatemia 01/2018
1	Chronic Kidney Failure (Chronic Renal Failure) 11/2017
1	Cystic Fibrosis (Mucoviscidosis) 01/2017
1	Steatorrhea 01/2017
1	Hyperphagia (Overeating) 01/2017
1	Inflammation (Inflammations) 11/2013
1	Kidney Diseases (Kidney Disease) 11/2013
1	Pyelonephritis 05/2013
1	Pyelitis 05/2013
1	Urinary Tract Infections (Urinary Tract Infection) 05/2013
1	Cystitis 05/2013
1	Disease Progression 05/2013
1	Persistent Infection 05/2013
1	Vitamin D Deficiency 05/2012
1	Hypercalcemia (Milk Alkali Syndrome) 05/2012

Drug/Important Bio-Agent (IBA)

21	CalciumIBA 08/2019 - 03/2002
19	OxalatesIBA 12/2021 - 03/2002
10	Calcium OxalateIBA 01/2019 - 03/2002
7	AlkaliesIBA 01/2022 - 06/2010
6	Citric Acid (Citrate)FDA LinkGeneric 01/2021 - 06/2010
6	calcium phosphateIBA 01/2019 - 03/2002
6	Uric Acid (Urate)IBA 01/2019 - 01/2009
4	AcidsIBA 01/2022 - 01/2009
3	Sulfhydryl Compounds (Thiols)IBA 12/2019 - 04/2005
3	Cystine (L-Cystine)IBA 12/2019 - 04/2005
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 10/2008
3	Phosphorus (Red Phosphorus)IBA 01/2014 - 02/2011
3	Amino Acids FDA Link 07/2010 - 03/2002
2	Ammonium CompoundsIBA 01/2022 - 10/2020
2	Sulfates (Sulfates, Inorganic)IBA 01/2022 - 01/2012
2	Bicarbonates (Hydrogen Carbonate)IBA 01/2021 - 12/2015
2	hydroxycitric acidIBA 08/2019 - 01/2016
2	Phosphates (Orthophosphate)IBA 01/2019 - 10/2008
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2017 - 02/2016
2	Parathyroid Hormone (Parathormone)IBA 01/2014 - 02/2011
2	sodium thiosulfate FDA Link 01/2013 - 06/2009
2	ApatitesIBA 10/2008 - 02/2005
2	Hydroxyproline (4 Hydroxyproline)IBA 02/2005 - 03/2002
1	Penicillamine (Cuprimine)FDA Link 12/2019
1	Tiopronin (Thiola)FDA Link 12/2019
1	Dietary SodiumIBA 01/2019
1	Pioglitazone (Actos)FDA Link 01/2019
1	SugarsIBA 01/2019
1	sodium phosphate (trisodium phosphate)FDA LinkGeneric 01/2018
1	sodium-hydrogen exchanger regulatory factorIBA 01/2018
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2017
1	Dietary Fats (Dietary Fat)IBA 01/2017
1	Bile Acids and Salts (Bile Acids)IBA 02/2016
1	Potassium Citrate FDA LinkGeneric 12/2015
1	Alendronate (Alendronate Sodium)FDA LinkGeneric 05/2014
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2014
1	MineralsIBA 01/2014
1	Dietary CalciumIBA 11/2013
1	Calcitriol Receptors (Calcitriol Receptor)IBA 10/2013
1	SaltsIBA 06/2013
1	Pharmaceutical PreparationsIBA 06/2013
1	Cysteine (L-Cysteine)FDA Link 06/2013
1	StruviteIBA 05/2013
1	Vitamin D FDA LinkGeneric 05/2012
1	25-hydroxyvitamin DIBA 05/2012
1	Ergocalciferols (Ergocalciferol)FDA LinkGeneric 05/2012
1	Urea (Carbamide)FDA LinkGeneric 01/2012
1	PotassiumIBA 01/2012
1	Calcium CitrateIBA 01/2012

Therapy/Procedure

9	Therapeutics 10/2021 - 12/2002
4	Bariatric Surgery 10/2010 - 02/2007
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2017 - 10/2010
2	Jejunoileal Bypass 02/2016 - 02/2007
2	Secondary Prevention 09/2015 - 03/2015
1	Complementary Therapies (Alternative Medicine) 10/2021
1	High-Protein Diet 10/2020
1	Renal Dialysis (Hemodialysis) 11/2017
1	Diet Therapy (Therapy, Diet) 12/2016
1	Urinary Diversion (Ileal Conduit) 05/2013
1	Cystostomy (Suprapubic Cystostomy) 05/2013